APPLICATION OF PLATELET-RICH FIBRIN (PRF) IN ORAL SURGICAL PROCEDURES

Platelet-rich fibrin (PRF) application in oral surgical procedures

Abstract

In 2000, Choukroun pioneered the use of platelet-rich fibrin (PRF). PRF is considered a second generation platelet concentrate. It is a fibrin mesh structure that stores a variety of growth factors and cytokines and gradually releases them during remodeling. PRF has a wide variety of applications in the field of oral surgery due to its biological potential to accelerate the wound-healing process and tissue regeneration. This review mentioned a number of possible PRF implementations in different oral surgical procedures. This review is based on the literature analysis of current oral surgical procedures including mandibular third molar surgery, preservation of extraction sockets, maxillary sinus augmentation, dressing, dental implant installation, osteonecrosis of jaw, oroantral communication closure, and periodontal surgery. These findings demonstrate that RPF can be employed widely in different types of oral surgical procedures.

Keywords: Fibrin, oral surgical procedures, platelet-rich fibrin (PRF).